https://video.chemcomp.com/watch/1bTgTN9fTd1DZ97FEuhnM4Pharmacophore Searchhttps://cdn.vidyard.com/thumbnails/39491800/FG_QQ0wxX_cEh8_pbruIkg.pnghttps://play.vidyard.com/1bTgTN9fTd1DZ97FEuhnM4.html?video_id=39491800&https://cdn.vidyard.com/videos/Z35_Xtqxq9exVjOM1Rw1nQ/hd.mp4?BNjNWQjrqXd5EziUy8jLl0770Pez5DyItzuWCRt0X9mhGZhYQQZMSXbmaFF4gO63Zw32RQXUdnO7fVLjMJOpBc44oCOf-FaxnwjYHWoJ530virtual screeningph4Pharmacophore EditorPharmacophorePharmacophore Query Editorsearchinghttps://video.chemcomp.com/watch/2VtMGBYvvMkumZqo8A3yJNFinding Druggable Binding Pockets Using SiteFinderhttps://cdn.vidyard.com/thumbnails/39491761/omn691iERks72LDUvR8keQ.pnghttps://play.vidyard.com/2VtMGBYvvMkumZqo8A3yJN.html?video_id=39491761&https://cdn.vidyard.com/videos/2ICJbAgwDDclaUTU9NHLTw/hd.mp4?L3e8vftASRywF0ypEjK53_vqGxYxofyN9fToMd7HWBwt5GW1xQgXjp3H9rwzGAIf04Hh-WXwHyxiKm3MWVA8qgVfMF4i-jtXlvkAM7Mi553DockDruggableBinding SitesBinding PocketsActive SitesAllosteric SitesSiteFinderDockingSite Finderhttps://video.chemcomp.com/watch/38NMzSKfDHQkph9LWPkuzJComputational Approaches for Optimizing the Developability of Biotherapeuticshttps://cdn.vidyard.com/thumbnails/40111695/q0qIlEVvc_2cYSQKXlz_jA.pnghttps://play.vidyard.com/38NMzSKfDHQkph9LWPkuzJ.html?video_id=40111695&https://cdn.vidyard.com/videos/M5I6fz_E4lVJdNsu36bQ5A/hd.mp4?cIHYaKc1KIm2eoOHZrLBusySI5DS1dCImVf6anV89y8DVKuiRvTFTBBgnx6KbYA6S9h0ApQJf59p5x7-opWjlyuQ4lkaG4o3XJeuCAAE2928Protein solubilityAggregationAntibodyDevelopabilityProteinsTherapeuticComputational methodsStructure-based rational designViscosity ThermostabilityHomology modelingHydrophobic patchesProtein engineeringProtein-protein interactionsChargeHydrophobicityResiduesSequence alignmentHIC column ChromatographyMutationsEnsemble structuresCDRsModelingConformationsComplementarity Determining RegionsRegression modelingpHProtonationwebinarhttps://video.chemcomp.com/watch/3WhEnZtfZiLvijBgG8yzgDSampling and Building Loops with the Loop Modelerhttps://cdn.vidyard.com/thumbnails/46512900/fKM3NO4MWkiE9eyI14sD8g.pnghttps://play.vidyard.com/3WhEnZtfZiLvijBgG8yzgD.html?video_id=46512900&https://cdn.vidyard.com/videos/ZyzbD33oGEEOX8u4wIcCCA/hd.mp4?KGe9CRci8h2qfS1FcIffwPz3W_UkszXc3ECYppML9eiTJSK8bBVJFCDswL72eYS7CY9qQ2PdzXslVsJQYntdiEc20x3hS7B4H6v8lJAZ287conformationshomologyprotein-protein dockinglooplinkerloop modelerlinker modelersample loophomology modelsx-raystructureshomology modelingloop conformationsantibody-antigenhomology templateantibody structurebuilding loopshttps://video.chemcomp.com/watch/4FVDZYATX5BJT7Cv52wHhN🆕 Rigid body Conformational Searchhttps://cdn.vidyard.com/thumbnails/47284841/cvJe5lMT_EPhbBZBNzDh7g.pnghttps://play.vidyard.com/4FVDZYATX5BJT7Cv52wHhN.html?video_id=47302535&https://cdn.vidyard.com/videos/OwNGwjr0PjDObhF-aoncgA/hd.mp4?Ophf6Jrr909i__bMSFTepRxTAhlwjoweUQspNBkOuCa_SCEvg2VmsKLEt1v_RicB4ZoxEORRWP07R1mfKCVTBQe4KdNx_Zf9wgdP_T7e607secondary structureconformational searchmolecular dynamicsprotein modelingenergy minimizationrigid bodyprotein structurehelicesmolecular conformationshttps://video.chemcomp.com/watch/4QuH8fJKD7AbrQGfmDXTfGMOEsaic: Mining Activity Data to Guide a Medicinal Chemistry Campaignhttps://cdn.vidyard.com/thumbnails/40112652/ir9_-XXkE3ak3joNkXOq_A.pnghttps://play.vidyard.com/4QuH8fJKD7AbrQGfmDXTfG.html?video_id=40112652&https://cdn.vidyard.com/videos/gbOUTlypjV1hKgWaZdNtPg/hd.mp4?PFQ1GXKGy-QdNIT5ZyXbfiJFnfoF1ZPTVlyLh8mpRN_fGPy2EXJtHyLmddXKpTUpjhfd4Vb8n8vPZiVBSWurgwCvQ14Ef1y_jFs40v1M2719congeneric seriesvirtual compoundsSARMOEsaicstructure-activity relationshipsvariantsMMP analysismatched molecular pairsInteresting MMPsMMP fragmentationMMP profileinvariantsFree-Wilson analysiscompound suggestionsFree Wilson analysisactivity cliffsR-group analysisR-group profilingSSSinteresting suggestionsMolecular SimilarityMOEsaic SketcherSubstructure Searchingdata plotproperty profilefilteringdefine alignmentfilterswebinarhttps://video.chemcomp.com/watch/57o8dZ2WCHkrsRrXqt1YKXAnalyzing and Optimizing Antibody Models using a Knowledge-Based Approachhttps://cdn.vidyard.com/thumbnails/40112085/9IPmXG4CHHXVw2YqEHch1A.pnghttps://play.vidyard.com/57o8dZ2WCHkrsRrXqt1YKX.html?video_id=40112085&https://cdn.vidyard.com/videos/TYrpdoCI8fCV-eoVKCzaMA/hd.mp4?5WuxzsVp6XXXPg4POzujvg_xz7SClhY9IvmRspYTDutFRfRWzoPvziqQSez78qcZeSwGmE1G9hMOQg-HVelAny9NQ-GF75D0T0usLEmq3143Protein PatchesProtein Patch AnalyzeraggregationAntibody Modelerantibody modelingantibodiesliabilitiesAntibody DatabaseMOEAntibody ModelingMining Antibody DataLiability AssessmentAntibody Database Project Searchwebinarglycosylationloop candidatestemplate selectionhttps://video.chemcomp.com/watch/5d1mTX9Ub9p7sjjsKCg2VqModeling Cytochrome P450 (CYP) Liabilities: Predicting CYP Selectivity, Reactivityhttps://cdn.vidyard.com/thumbnails/40550147/a-v0atyswtw7tg1jVjoopg.pnghttps://play.vidyard.com/5d1mTX9Ub9p7sjjsKCg2Vq.html?video_id=40550147&https://cdn.vidyard.com/videos/OlQqqlu6q7yE_RYi7hpOMA/hd.mp4?vsqG9LVk7IOBN0Y2dgWWoddj9Y1etWQSR9JPGaLmuiMQ3fUstFwVYxUrHItfoY4Um6zwrwzMg4c5bAB2WDFlCY3sKXd6FzUXx1Ryouwg3507PharmacophoreSites of MetabolismMetabolismCytochrome P450LiabilitiesCYP ModelingCYPswebinarhttps://video.chemcomp.com/watch/613C9ndY8tQ3YHqEyp7YYm🆕 Computing properties of polymers using Polymer Propertieshttps://cdn.vidyard.com/thumbnails/47933037/5WxgnfojyHpBDAl9jE4JDA.pnghttps://play.vidyard.com/613C9ndY8tQ3YHqEyp7YYm.html?video_id=47934884&https://cdn.vidyard.com/videos/la0PRZnqbnfl8ieJRdmQbg/hd.mp4?LFKFb7RxORWdTTeGtJZzPhcKXb8O2ks2A7e5OQEHCJQzydCHqgs7F8-4yKIRaN9mAoOvMI5j3Ukhc3AiOFl_SJfggMc73f2HZXbgXj4x164polymerpolymer propertiesscalarscalar propertiesPolymer Property PredictorPolymer Properties panelcomputing propertieshttps://video.chemcomp.com/watch/6dGEChdi82ZfRr1XrV1JrYAdvanced Small-Molecule Dockinghttps://cdn.vidyard.com/thumbnails/40111344/p8QlS8eA5rS3Arq1oqas5w.pnghttps://play.vidyard.com/6dGEChdi82ZfRr1XrV1JrY.html?video_id=40111344&https://cdn.vidyard.com/videos/nVO1oRkbu1s7Ut9cuzUo0A/hd.mp4?NmYoBJzFBdoPJvI6VCjqwTbsbwr3c_zltAeQpisofRZ601q6-izbdAOxGsCBooFar77pLnXz47DD2y83U7vB-BYNkPBLmPcEnUZrqjVW3219dockingDockingPharmacophoreTemplate-Based DockingCovalent DockingGeneral DockingSubstructure DockingVirtual ScreeningDocking Scorewebinaradvanced data browsingligand-receptor interactionhttps://video.chemcomp.com/watch/7oWHYE5gJDBatn691yUhafStructure-Based Molecular Transformationshttps://cdn.vidyard.com/thumbnails/40111074/7FrasqBN8t-ngluiYeqevw.pnghttps://play.vidyard.com/7oWHYE5gJDBatn691yUhaf.html?video_id=40111074&https://cdn.vidyard.com/videos/jDcRnW7dwBNYBxNEz4JtTw/hd.mp4?9aHWn4aQQcl2NATAUL51v2M13_HuHy4BsI-D0H-pTVXZNT-ORoB5N5zwGrEmrqDp0uGWH6nOP5mV63MLWDgVmvELW5ExzaY_OQgMfeUr3278Pharmacophoresmall moleculeHomologationlead optimizationsbddmolecular transformationAnalogs Heterocycle substitutionBioisostercyclisationNc switchAffinity ScoringFocused librariesSynthetic scoreHalogenationMedicinal chemistrysmartsProtein-ligand interactionsFragment toolsInteraction surface3d filterquickprep3d embedding2d filterwebinarPDE5https://video.chemcomp.com/watch/81viuCfy98DoviH6p27b8p🆕 Building copolymers using the Polymer Builderhttps://cdn.vidyard.com/thumbnails/47920215/gwSgw3yXMb7RczHFYmwLvw.pnghttps://play.vidyard.com/81viuCfy98DoviH6p27b8p.html?video_id=47920215&https://cdn.vidyard.com/videos/mG7a8HwZF8MTejGVV842jg/hd.mp4?HG_EvYsI9Z1l7BQDzqOIfsKc_4w9JPnsGznKk0bsWfJ1sOpDcGXvZPkcyOCvSfshXa1la6_En0-ivW5wF0zD8YwSHbSbaNlTp4-JHr4E247MOEPolymer BuilderPolymercopolymercopolymer buildermonomersstatistical polymerhttps://video.chemcomp.com/watch/8FUbiYN1Pbv7ZjwYvJxQtEIntroducing CLE: An Interactive Web-Based Combinatorial Library Enumeratorhttps://cdn.vidyard.com/thumbnails/40549790/urmvijDmf1fmIV1rZcAZRA.pnghttps://play.vidyard.com/8FUbiYN1Pbv7ZjwYvJxQtE.html?video_id=40549790&https://cdn.vidyard.com/videos/otnDsZiolIpLRKi5JPvDbA/hd.mp4?8jq2dzKz_sB-q9Dv0cIC_FnvUByRxdrEXuud1So79EB0t6P4fTn2WV0dySAuWuguFEOiftL4__1kN8XiSpdG4b8nJ7hMusTocpeGkM_41368reactiondescriptorsCLEreactionbasedchemicalreactionsynthesisplaningchemicalsynthesisenumerationlibraryenumerationcombinatoriallibrarywebtoolbrowserbasedmolecularmodellinginsilicoqsarsarexplorationchemicalspacestructuralanaloguesfunctionalgroupsvirtualcompoundsbuildingblocksclickchemistrydrugdesignmodularmolecularfiltersocussedlibrarywebbasedwebinarreagent selectioninteractive web toolproduct filteringhttps://video.chemcomp.com/watch/8eeJ1WUVBceNKKUAWorXTEPreparing a raw PDB file containing multiple ligandshttps://cdn.vidyard.com/thumbnails/39492887/-7ZxIyX3Pd5ndJneqtedmA.pnghttps://play.vidyard.com/8eeJ1WUVBceNKKUAWorXTE.html?video_id=39492887&https://cdn.vidyard.com/videos/NiuylWaafyZb57uZ39ACEA/hd.mp4?7HpVO8nUY39ikGGyNoGpz4p-Ti1PpFiCFNpKYXHDGGbJilfs9n9pbHJyrj5AzK27l_BEaZpjkDj0OWYLc41Fg1eT9wv24UIhKFezjGuw385QuickPrepPDBstructure preparationprepareChoose Ligandprotein-ligand complexhttps://video.chemcomp.com/watch/96b4D4oTaCP24dGyMrNZ2wRevealing Conformational Behavior in Solution through NMR Data Analysishttps://cdn.vidyard.com/thumbnails/40112948/Wg6Wq5iBKSAIlqAXMBadAQ.pnghttps://play.vidyard.com/96b4D4oTaCP24dGyMrNZ2w.html?video_id=40112948&https://cdn.vidyard.com/videos/0lkASo-cwnTTw1PMrQFUfw/hd.mp4?k2LuEAOpTWgoT79eJXTnL0_VHIPUp1XZQQ0SKN9fuHHuwJ4nbc_kdK-JPlsgHF4534zrUr_Qt_8m2i5PYu_atKnY48ma_tAkQIZAHQQC1721conformations/conformational searchLowModeMDQMNOEmacrocyclesexperimental dataNMRspectrum/spectraGAUSSIANBCL6couplingwebinarLow Modeconformational behaviorNMR data analysisBCL6 inhibitorhttps://video.chemcomp.com/watch/9ofxx8WgKD57XUawhdTWyRSampling and Building Linkers with the Linker Modelerhttps://cdn.vidyard.com/thumbnails/46927492/-1LXUNoCtej5OxjtSvKBDg.pnghttps://play.vidyard.com/9ofxx8WgKD57XUawhdTWyR.html?video_id=46931562&https://cdn.vidyard.com/videos/qIUiZNFWmvfT0o81xA8drQ/hd.mp4?D7-khig7azwAeLk7lYL70OlfyAxHjUth6ljbadTpzRlOcwjqndaCBuyo-Scv6thoWjVpv6knsSUlOuN69YSRk04srJ2fC_h7rnSiLjnT317protein engineeringconformationshomologymolecular modelingprotein-protein dockingLinker Modelerhomology templatesantibody designSCFVfusion proteinsCDR loopslinkerhomology modelingantibody-antigenhomology modelerlinker conformationsantigen-bindingscFVsingle-chain variable fragmenthttps://video.chemcomp.com/watch/ATS4joNLDtBCHGz9Chm68GReverse Fingerprints (III): Ligand-Based Pharmacophores and Virtual Binding Pocketshttps://cdn.vidyard.com/thumbnails/40550050/I3uprytFXa4liAuVk-QU4Q.pnghttps://play.vidyard.com/ATS4joNLDtBCHGz9Chm68G.html?video_id=40550050&https://cdn.vidyard.com/videos/ZuwUVacmKeJW8wl_Oge1Wg/hd.mp4?RE6mVqWN64Hrl0RHnliXqiV1XexqpV3Wb-Okf509xM-TiEBq8CNFzj-Feh4XB6Syqthl5Mf2VzvRZdn0X1LiDRB80Hq09bEOu0yXKpzO2022Ligand-Based DesignMolecular FingerprintsPharmacophore searchingpharmacophore queriesvirtual binding pocketsmolecular modelingwebinardrug discoveryligand-based drug designpharmacophoresreverse fingerprintsvirtual pocketsconsensus pharmacophoresligand densityhttps://video.chemcomp.com/watch/Ajj1hLwRBd53ydCqxcx5kEPeptide Binding Analysis and Optimizationhttps://cdn.vidyard.com/thumbnails/42495533/CMLmVH5rvhgxXOWmMk9eKQ.pnghttps://play.vidyard.com/Ajj1hLwRBd53ydCqxcx5kE.html?video_id=42495533&https://cdn.vidyard.com/videos/g01-9eVV4oRzAf4xsyB72w/hd.mp4?iuih59GQrWKAFDierILN0r4AdSxFqYOAph-Ru1439EIt8kVaQ6qAldJDakuXZuLak9P-gqfqyRzsglYWwmtVDvp3l-keTcbKMxfz7GA83229electrostatic mapsPeptide ModelingStructure preparationmolecular surfaceDrug DiscoveryCCGCADDMolecular Operating EnvironmentPeptidesChemical Computing GroupInteraction analysisPatch analysisProtein propertiesProtein contactsVirtual mutagenesisP53protein interactionMDMXpeptide bindingsmall molecule builderprotein designmutagenesisaffinity calculationscustom amino acidswebinarhttps://video.chemcomp.com/watch/Any7cKe72zyTBmSDsDUpsGCombinatorial Library Enumeration for Structure-Based Drug Designhttps://cdn.vidyard.com/thumbnails/40110932/haT2rE6_lhtMzC9-FwPEhw.pnghttps://play.vidyard.com/Any7cKe72zyTBmSDsDUpsG.html?video_id=40110932&https://cdn.vidyard.com/videos/-mb1sab4trYsGseduyfwSg/hd.mp4?y4T7uSMWic_sJpyZFytMMUqx-i4ZGZx38w0f-2o2BihQTB0oocR0Vj9yVyuQMqfjhEB9pRUkzjNEDEqXWsk2MFjen04x_InVAARNShEt2590chemical reactionscombinatorial libraryvirtual screeningfragmentsstructure-based drug designpharmacophoreCLElibrary enumerationreaction-based enumerationfragment screeningfragment toolscombinatorial builderbuilding blocksdatabasespharmacophore filterconformation importclipping reactionconformational searchBuilderlabelled linkersEGFRwebinarEGFR inhibitorshttps://video.chemcomp.com/watch/AofbRr6kaU44y5HyFTXy9mPharmacophore-Guided Dockinghttps://cdn.vidyard.com/thumbnails/39490913/lSQd4o2_a2Q0nxjX4VKI1A.pnghttps://play.vidyard.com/AofbRr6kaU44y5HyFTXy9m.html?video_id=39490913&https://cdn.vidyard.com/videos/COf_aXSNlmQ3lAQOF8v4mA/hd.mp4?F1vYPdVcfwTLviJiU827OUN-u4HZ2BMMShugmI-KG7sBkbaUHO8MVb92-mz7OEVkYCnqdT5IzH4BhuN68CZj7qgdpKztSa_8CQ1ZpYyH1124Dockscoring functionbinding pocketscorescoringactive sitevirtual screeningligand interactionsgeneral dockingpharmacophoreph4induced-fit dockinginduced-fithttps://video.chemcomp.com/watch/BmS4qBaVgcKGgsAaXbbv6cPreparing an SDF file for use in MOEhttps://cdn.vidyard.com/thumbnails/39492803/dZyAtArqIucE5iQDo4neyw.pnghttps://play.vidyard.com/BmS4qBaVgcKGgsAaXbbv6c.html?video_id=39492803&https://cdn.vidyard.com/videos/4aujV7N296SvEHZzC31L8A/hd.mp4?I6hg6suU3NJLHtWWzD_jqkKfjA9VqEBWx-Pz4VPkH_qExFibP9m3rmqQFwdpBLUAhSVtnNZiMVfgm9Nr-Tv2jSqKJnDzPImTl8IYg_2n338protomersprepareDatabase ImportpreparationwashingSDFprotonatecleanCSVDatabase Washprotonation3D2Dhttps://video.chemcomp.com/watch/CJfaKWsYWZmiHhUaJoe64TPerforming Solvent Analysis on a Protein-Ligand Complexhttps://cdn.vidyard.com/thumbnails/44948371/plv7wONkuqNgosxpRj1Xqw.pnghttps://play.vidyard.com/CJfaKWsYWZmiHhUaJoe64T.html?video_id=44949518&https://cdn.vidyard.com/videos/-TZldrsVH2rKeB3-bdXbEQ/hd.mp4?NhJbcIfAju_7KT2lOMONE55uGsl-yK5VKpEDqqXTFNBAI0KgE4m9nDO8zxv6H-TzpJ31wIPDkl3XfgPM_40Ruxy5dpKWkldS7nOgPF32569simulationSolvent AnalysisProtein-LigandReceptor modeComplex modewater moleculesreceptor modeligand affinitycrystallographic watersligand bindingRISMhttps://video.chemcomp.com/watch/DRiop6S1W9B2jFqusPP6tHHomology Modelinghttps://cdn.vidyard.com/thumbnails/45843350/m5xqNz_kpKZz-e7IhGQ8Iw.pnghttps://play.vidyard.com/DRiop6S1W9B2jFqusPP6tH.html?video_id=45843350&https://cdn.vidyard.com/videos/2Feb_70dFn5laOz3ACzjCA/hd.mp4?CSrP7FrxGEFodg5aFUCJdei0o1e0KgrXLsI-9ghxOP7IVaB4C200cAjuSirQt_7X3OILUlB1m2uU4s_qY_YC1G_49eCvhx3QUimD9Byc624Sequence EditorStructural BiologyhomologyProtein StructureSimilarity MonitorTemplate AnalysisModel QualityProtein Data Bankhttps://video.chemcomp.com/watch/Dh14rf5UWDfwHVN1sybuMG🆕 Efficient Conformation Search of Protein Loops using LowModeMDhttps://cdn.vidyard.com/thumbnails/48247796/W2kt6xdJpvB9yeuGCQAwaA.pnghttps://play.vidyard.com/Dh14rf5UWDfwHVN1sybuMG.html?video_id=48247796&https://cdn.vidyard.com/videos/jDk7huEmPvI8GzbRhk34qA/hd.mp4?tMKh_6MbW-2oI6p67_y4RW8PErAkBcLg1O2bFDaMzinihSMojVv2Kso18v4bY5Sdmifgbd_rKzbpKTqs7VAlP44ejyO02jgZ9SMHZGbW486conformationsMOEconformational searchLowModemolecular dynamicsprotein modelingenergy minimizationccgchemical computing groupP-looplow-mode MDLowMode MDstructure analysisligand interactionLowMode SearchMD SearchChiral inversionshttps://video.chemcomp.com/watch/DxGEUNY8kzzruXuhfo8KMUFinding key contacts for a protein-protein interface using Protein Contactshttps://cdn.vidyard.com/thumbnails/39493055/l6qraehCzwRWa_exqYMQog.pnghttps://play.vidyard.com/DxGEUNY8kzzruXuhfo8KMU.html?video_id=39493055&https://cdn.vidyard.com/videos/y11hCTvmu2A6qMzx2eEs2g/hd.mp4?_0EmaW7ozGDpZfZGuZXM37kX64a_G0RsJfZsQLnG8h4Ag5LXuHdU4NY6NsR3Qfli5hiIASYLfT-nHO3Lgi73YZF1MUXE-93RPIV775vW517Protein Contactsprotein-protein interactionsprotein-ligand interactionsprotein-peptide interactionshttps://video.chemcomp.com/watch/EH7iZ92cGsZQfqpCrxNRceNew and Enhanced Features in MOE 2024.06https://cdn.vidyard.com/thumbnails/44873950/IOuFvEq-fS2CPBDkQI96tg.pnghttps://play.vidyard.com/EH7iZ92cGsZQfqpCrxNRce.html?video_id=44873950&https://cdn.vidyard.com/videos/A_JWC39dHuNejAmHtSZmHw/hd.mp4?maYQpzdA1MV0ucT2YhBjIBws7pkQwFNIdfJmwxjGlOmSFZxV0of6fLyfU7byPRK25IuQEPYnCAgzzo9_L5pzeBsm_D38P6rZMjDz2my32737AMBER:EHT ForcefieldCapture Design IdeasRNA ModelingHigh-Throughput Biologics ScreeningR-group-Activity-Relationship Heatmapswebinarhttps://video.chemcomp.com/watch/EMycRzwHV2hoCkro5GXEAQAmberEHT Forcefield: Novel Approaches to Small Molecule Parameterizationhttps://cdn.vidyard.com/thumbnails/45067264/sY2Y2VFilMxk15Y1-BuI8Q.pnghttps://play.vidyard.com/EMycRzwHV2hoCkro5GXEAQ.html?video_id=45067264&https://cdn.vidyard.com/videos/OhJgCfvMJ9BHUiSGf-BMWg/hd.mp4?mPrxjVt3VVlBYTrztMJeqnuSd4585yEH80pbB3WgYdArV_9pgb6kDijgb2J4nFN9fmBIejOqoTYJq2gl7-DVl5cgmWv3cACNqQftMKVB2158Drug DiscoveryCADDMolecular Operating EnvironmentForcefield ValidationForcefield DevelopmentForcefield ParametrizationAmberEHT ForcefieldAtom-type Free Parametrizationsmall moleculesforce field parameterizationmolecular dynamicsEHTHückel Theorywebinarhttps://video.chemcomp.com/watch/EtjHHogobxBr8EXA7ddiVRFragment Based Drug Design - Scaffold Replacement; Select R Atomshttps://cdn.vidyard.com/thumbnails/39492083/dsxoHLYDHIfc0EAgPSELZg.pnghttps://play.vidyard.com/EtjHHogobxBr8EXA7ddiVR.html?video_id=39492083&https://cdn.vidyard.com/videos/VkWx4s8uqU4f5EjZD1qcGQ/hd.mp4?_5XdQcnumsEXl3Gh4ZB7nyHejP2aN-G5BZfpZL-l_S06Vsgzwsb7VbUsTyHye88L1rYDheRIwZQp-PVZNDDK-rcXYqUT7ij23WTxy5lH662analogsanaloguesfragment-basedfragmentsFBDDlinkersscaffold hoppingsubstructurescaffoldshttps://video.chemcomp.com/watch/FPcDscZ38zLTWxbvMsNRryUsing Structures from Cryo Electron Microscopy for Drug Designhttps://cdn.vidyard.com/thumbnails/40110923/oZzifqLZMuNhetktHalVPg.pnghttps://play.vidyard.com/FPcDscZ38zLTWxbvMsNRry.html?video_id=40110923&https://cdn.vidyard.com/videos/p-yN7GB4wu6wI7j6hQ5HCg/hd.mp4?InVdZ-Lmo-YDmOa4bONHHeVkgQMJdNCAyDavIJlv1EUEW7Jtnv0FtVP8Vmbnly7kB9tqTnwaMMQUD694e1pGoazlz8oWWlcJmjevfRSm2169protonationStructure preparationProtonate3Dhydrophobichydrogen bondspi stackingCryo EMhydrophilictopologyelectron density mapchain breakshydrogen bondingloop modelingmolecular surfaceligand interactions diagramwebinarhttps://video.chemcomp.com/watch/FRxEyZNQucvCSkEB5Zzp31Creating a storyboard and tracking design ideas using Capturehttps://cdn.vidyard.com/thumbnails/45138355/61TXni7F55hDOcfsbVaxKg.pnghttps://play.vidyard.com/FRxEyZNQucvCSkEB5Zzp31.html?video_id=45229952&https://cdn.vidyard.com/videos/6hL0MqwKtdJIcTsxks4PqQ/hd.mp4?NtlWpHveJKLC4Z9QnbuFUOsH4A_S0BQR3H3P27xoBaH5wq-YsmAbUQbig_IFKRCrpsDykxeB-kZFEWn1IgEUttUIUVpLNcuZ6UOy-Lte359binding pocketstructure-based drug designelectrostatic mapsMOEStoryboardCaptureSBDDaffinity predictionligand propertieschemical modificationshttps://video.chemcomp.com/watch/GLwFJgp5tyTUxB8xrJd2Z4🆕 MOE license server installation for Linuxhttps://cdn.vidyard.com/thumbnails/46954015/IISHOLz0thCq9n8L5ntnlQ.pnghttps://play.vidyard.com/GLwFJgp5tyTUxB8xrJd2Z4.html?video_id=47071245&https://cdn.vidyard.com/videos/tBa9KzZi-IOeQrPSSMFTvQ/hd.mp4?lMEiNN1aJW8ygqnKpc3OnXThMlWNYkVQP8zIMP8ttTG5di5qjUNm6mPjVcRekJGCj3K0_gld7avUJdo_fGtVQbqP4NyxYZcvRqMBZ_c7419MOEinstallationlicenseLinuxlicense managementsoftware installationnetwork setupMOE installMOE serverFlexNetFlexLMhttps://video.chemcomp.com/watch/Gfz955R2KAyqcGGZ8iwEfcReverse Fingerprints (I): Motif Detection and Activity Labelinghttps://cdn.vidyard.com/thumbnails/40550082/yuUY8wbGQ9Lmja4t61YHuQ.pnghttps://play.vidyard.com/Gfz955R2KAyqcGGZ8iwEfc.html?video_id=40550082&https://cdn.vidyard.com/videos/-nMVENHR-_qYHCrnACUbVQ/hd.mp4?ZRzFVr0qrFTP6-LM1qGIgod9s0PyuPjGCegdyL0BX6MGrYgKTpnqgrzqjfwDeV9OiCLzDYXVVdNSVf3tK3QTFsEZUkgry_L7JiS5SJZb2529Ligand-Based DesignSAR AnalysisVirtual screeningMolecular FingerprintsActivity visualizationCheminformaticswebinarmotif detectionactivity labelingQSAR modelstoxicophoreshttps://video.chemcomp.com/watch/Ha6MTVjChEbraEfx7pjPrJSuperposing Proteins on Structurally Conserved Regionshttps://cdn.vidyard.com/thumbnails/39491514/2YBxeMHtENzJWVxXMkjhFA.pnghttps://play.vidyard.com/Ha6MTVjChEbraEfx7pjPrJ.html?video_id=39491514&https://cdn.vidyard.com/videos/ygw1zRMma--eem-93nBeiQ/hd.mp4?6TDy1RYmFcMpMs5SOD45-cv0EvNZaOJ1K9nR89mpwO-sEnFFp3HtwgwNwEnAutfOa9zQJY7c5PKu8mJXoiUYNOpesUaFFgkZ_O72qDO2444alignmentAlign/SuperposealignsuperposingaligningsuperpositionSequence EditorsuperposeSEQhttps://video.chemcomp.com/watch/Jh1cNy4BGJEDYyuP3WpqBKProtein Surface Charge and Hydrophobic Patch Analysishttps://cdn.vidyard.com/thumbnails/40112600/3WLqmT8cuMfWThRdZw19ew.pnghttps://play.vidyard.com/Jh1cNy4BGJEDYyuP3WpqBK.html?video_id=40112600&https://cdn.vidyard.com/videos/DCmAtutxyXnohO4fmT6L7g/hd.mp4?uDkv1cOCFP_iQrKeldV4Gk0lyjKrpA64Nkjqb4M8DcsBcO4M5P6bWd4rwSQCGtsg_XUAUfbwHOXFdj4zWlB-FPt-MjBAhCvjW0Zvii_l2017Protein PropertiesHydrophobic patchesHydrophobicityBiotherapeuticsProtein Surface ChargeHydrophobic Patch AnalysisAggregation propensityViscosity In silico predictionsAggregation-prone regionsProtein SolubilityEpitopesCharged regionsProtein-protein dockingBiophysical propertiesEpitope mappingEnsemble of conformationsAntibodiesPatch descriptorsProtonation stateFlexibilityHIC Retention time2D MapsPatch Analyzerwebinarhttps://video.chemcomp.com/watch/JrR21mLpYyEqo52UTbEcAREasily Access, Analyze, and Manage AlphaFold Structures in PSILOhttps://cdn.vidyard.com/thumbnails/40549938/n253uSS6xvl_l_DMyj4dbw.pnghttps://play.vidyard.com/JrR21mLpYyEqo52UTbEcAR.html?video_id=40549938&https://cdn.vidyard.com/videos/bz0mVQ3x2CNpfelBWyrjtQ/hd.mp4?9Yg8xnBetvYQNmycRaSsTl9LiUe5oK4bF8Gi_sXVh42mzBqrUf3H6oldjaYqOY-ItpXSHfQLUNuCCPuOmY86wwP3R0HVS4fD9q5OiWm33211PSILOAlphaFoldstructural datadata visualizationwebinarstructural biologyfederated databasemacromolecular repositorydata managementqueryingstructural validationbioinformaticscheminformaticshttps://video.chemcomp.com/watch/JyRiViCVmxGtNfbEye2tKtMOE Database Viewer: Advanced Molecular and Data Visualizationhttps://cdn.vidyard.com/thumbnails/40110281/4my5B0cSXn08A1Bh-06PWA.pnghttps://play.vidyard.com/JyRiViCVmxGtNfbEye2tKt.html?video_id=40110281&https://cdn.vidyard.com/videos/TxhZO4NODTCDZvAMHK6f7w/hd.mp4?wKkdeUAAbS0wETSISY-CYMInUXiDUz9KjIYFmTmtfMCde1Tc4aOUtV61iUv1laX0TuQ0YfK1GyjoNiGrEUG6vDcWkPuAf7PZqs-lDUQG3512propertiesDatabase ImportSDFCSVdatabases2D depictions3D depictionsDatabase Viewercarbohydrate SNFG displayDBVrenderingDatabase BrowserDatabase Viewer Field Coloringdata plotscolor gradientscoloring rulescolour gradientscolouring rulesdata plottinggraphicsimagesdata analysispictureMDBWashdisplayCalculate Descriptorsdata precisionMolecule NameField HistogramsData PlotsSend to MOEhttps://video.chemcomp.com/watch/KAfWEisCNjgwPhvARjbjLeProbing the Psychedelic Structure-Activity Spacehttps://cdn.vidyard.com/thumbnails/40549680/ZlcxW5iuiEojT_usQ0vSjw.pnghttps://play.vidyard.com/KAfWEisCNjgwPhvARjbjLe.html?video_id=40549680&https://cdn.vidyard.com/videos/FX7TsgQTw1drTTIWcpTrGw/hd.mp4?p0avRyB7A1sDqMXA0GO9dj3fAfeP5Yv7JhZuv5sjgu2cnm-UCj_4I0l8zH_-3_az7uHuyUK5gkN3tvGQPTt5V1Y7gPOtfVGay6pXkxmg2525DockingSARPsychedelicsLigand-Based DesignSAR AnalysisPharmacophoresStructure-based Drug DesignVirtual screeningwebinarstructure-activity relationshippsychedelic drugshttps://video.chemcomp.com/watch/KJXpfRBD7iQzVaugSniW9MCLE: An Interactive Web-Based Combinatorial Library Enumeratorhttps://cdn.vidyard.com/thumbnails/39491152/usv08YsMuXSDIDSz5COnTA.pnghttps://play.vidyard.com/KJXpfRBD7iQzVaugSniW9M.html?video_id=39491152&https://cdn.vidyard.com/videos/qPs1KrG9JMgP55ls-VT_KQ/hd.mp4?Z5iwZFVdO5quPJfM23QsYuCG_hYTnLRP6Y6kmnyGd4lkJ2VYf9LTyJmOXWK-b-BNCJGVJDGHnAExlxH3f780U1I46tb5ysb6uI5hhQiA833reagent catalogschemical reactionsreagentscombinatorial librarycombinatorial enumerationanalogssketcheranalogueshttps://video.chemcomp.com/watch/Kmi6vZDKVM96azQW87jBKdEnsemble Protein Properties and Liabilities Analysishttps://cdn.vidyard.com/thumbnails/46143015/fDP16tafhuxgdk9lEtEWdQ.pnghttps://play.vidyard.com/Kmi6vZDKVM96azQW87jBKd.html?video_id=46143015&https://cdn.vidyard.com/videos/noMWE5CdNfhepammQEryLg/hd.mp4?n-4dNrCDhUcKnfEL-eGjK7gF84yqEGx1FdmEAVLZqqA-xBimZzwmmmU8ni7yhYEIb_DfdOhJqclDuIzgn0U8NRASkh-Zk-E046EqarIB468solubilitystabilitypHviscosityprotein propertiesensemble averagedeamidationmolecular descriptorsstructural analysissolvent exposurehttps://video.chemcomp.com/watch/KpUci4gFpDdBPjPA7u3fd3Modeling Targeted Protein Degradation via Bifunctional Degraders and Molecular Glueshttps://cdn.vidyard.com/thumbnails/40549683/tyTjVYrp3IJLfugc4QkVjQ.pnghttps://play.vidyard.com/KpUci4gFpDdBPjPA7u3fd3.html?video_id=40549683&https://cdn.vidyard.com/videos/56uEw5BXGCYaYqu3QjcgoA/hd.mp4?X0vtvFlqCCsSLT504gTvdwyNttcCpHPxduWpHLe6AimJqiXlTO7Q0GC_e2CTO4331IZxK9Xyo9YP0Ysi4_f-VYuwd3soRlAi0x64DzAO3199protein-protein interactionsHeterobifunctional DegradersTernary ComplexesTargeted Protein DegradationMolecular GluesMethod 4BProtein-Protein DockingBifunctionalsPROTACsprotein dockingcomputational biologywebinarhydrogen deuterium exchangescoring methodshttps://video.chemcomp.com/watch/L7XGTNkDnLPDdpv4eoUrqaHow to Build an Fv model from sequence using the Antibody Modelerhttps://cdn.vidyard.com/thumbnails/39492520/MM4IPU_aKP_iPhOsq8cW5g.pnghttps://play.vidyard.com/L7XGTNkDnLPDdpv4eoUrqa.html?video_id=39492520&https://cdn.vidyard.com/videos/CjMQ-uPAUIb5C0WuPDj0Hg/hd.mp4?yXunwBYKyiK34IrvLaMqOmkhbE8lnxotaVCIOvaVujLv_4uPIMcfPj9UF7jE7NTybiiWYLRYIN9f2l8MbUuQHdDHBn_zqD3BCsAp9wHP381FvAntibody Modelerantibody modelingantibodiesFabhttps://video.chemcomp.com/watch/LPE4fGMANxfZxerMPcM5GgInteractive Structure-Based Peptide Optimizationhttps://cdn.vidyard.com/thumbnails/39493244/G0ypiTC0ZqGYhwsXCS8RcA.pnghttps://play.vidyard.com/LPE4fGMANxfZxerMPcM5Gg.html?video_id=39493244&https://cdn.vidyard.com/videos/dZdT4jJR-wKr6VCNoxqztQ/hd.mp4?JDYKhR8BPMiGwbL9jKCssXSscNnKi9s-9dzJ47rYYsCXFjbEmdFdM406VVR_HFcpwAov-KhkaKy6SLCd04-QKnQ3eapzLQr6po4QJJPl1247Ligand InteractionsContactsProtein PropertiesProtein Buildermutatemutationsoptimizeelectrostatic mapspeptide optimizationPeptide-ProteinProtein-Peptidepeptide designPeptide Propertiespeptide interactionsLigand PropertiesSurfaces and Mapshttps://video.chemcomp.com/watch/MEVPLM2MWLYe8AxVTYrjM5Speeding up calculations with Parallel Processinghttps://cdn.vidyard.com/thumbnails/42589782/eypYsrgPI3o2svHgtk2orw.pnghttps://play.vidyard.com/MEVPLM2MWLYe8AxVTYrjM5.html?video_id=42817232&https://cdn.vidyard.com/videos/5jZn-fTll9seunfhXTk6YQ/hd.mp4?ZUKCLrJBNuecv7u6XYB9qWd0KlFd3bofZjwXNV4mbexPm3LmDqKwn7Zr9kzoD4NQSJT4Hnb-nSasXL9oLR3aJ4tPFJZM80ZePLhe5xhZ377parallel processingMOEwebbatch calculationshttps://video.chemcomp.com/watch/MfQMdvjSFikYTbJSb1bA4GMolecular Visualization and Publication-Quality Graphics in MOEhttps://cdn.vidyard.com/thumbnails/40109901/MFTGPdKdoELeoYCNQbcfxQ.pnghttps://play.vidyard.com/MfQMdvjSFikYTbJSb1bA4G.html?video_id=40109901&https://cdn.vidyard.com/videos/xEk18qb9hjQfmf094Ca9kQ/hd.mp4?j2k_EzEvif8-uXC7FJ_P7xTBCdQ2RiTH05CS8fozfQ5MtfqaJpxQOdlP07RYwd2X0BXiHg08sZyj6NthwilOVkCChm2Jcf3I0GgPsDb53477renderinggraphicsdisplayribbonspublicationsvisualizesurfaces and mapsvisualizationvisualisation3D printersobjectsvisual effectsvisualise3D printingmaterialscolorslightingcoloursbackgroundsfile formatstransparencypresentationsVisualization SetuptransparentexportingLigands InteractionsfogzclippingMouse Reference Panelzclipz-clipanti-aliashttps://video.chemcomp.com/watch/N8fufHcUK8qiu2qgVT74FUReverse Fingerprints (II): Fingerprints to Pharmacophore Querieshttps://cdn.vidyard.com/thumbnails/40550075/_2aPnTsU1tZQkppCnUaSSg.pnghttps://play.vidyard.com/N8fufHcUK8qiu2qgVT74FU.html?video_id=40550075&https://cdn.vidyard.com/videos/s5v7QksV6iumIUXo6LRsDg/hd.mp4?7uyq9COHUirzO9rumZHQoJ_R-CODQdOGh3BwTqwFxESgnNAUk0BfhSWgetFfvCPVk1vYgpR6gxek8Ww9KK9z762ll0DXGx6kNTBnOCDA2419Ligand-Based DesignVirtual screeningMolecular FingerprintsPharmacophore searchingpharmacophore queriesmolecular modelingwebinardrug discoveryconsensus modelingactivity scanningcomputational chemistryhttps://video.chemcomp.com/watch/N9MXH9HbpTnENUWUswcxDESolvent Analysis for Lead Optimizationhttps://cdn.vidyard.com/thumbnails/40110722/lzo2TND1OgyMr96Gts5aYg.pnghttps://play.vidyard.com/N9MXH9HbpTnENUWUswcxDE.html?video_id=40110722&https://cdn.vidyard.com/videos/DCtoIXSeuQPvCl3YdHb2-A/hd.mp4?tZplshv5CcYRVSIk4X0o4wRCZmBxMF9GrgQf2VRdrvScPuvziQF8YfHzoODmTqcjpP6i5pY7TQF4MPqnXV1q05BavRDTTzfcGDvjOpPu2795Water Placement3D-RISMWater PredictionSolvent AnalysisLead OptimizationSolvationDisplacable WatersWatermapwebinarcomputational chemistryprotein data bankhydrogen densityprotein-ligand interaction3D RISMwater localizationligand efficiencyhttps://video.chemcomp.com/watch/NfAvVkmPdoFUQ4QxVA6PNqPreparing a raw PDB file containing a Protein-Protein complexhttps://cdn.vidyard.com/thumbnails/39492965/j2fbUet9qifI3TiJ51eskg.pnghttps://play.vidyard.com/NfAvVkmPdoFUQ4QxVA6PNq.html?video_id=39492965&https://cdn.vidyard.com/videos/_OHOQ3I1TEdgx-w0pngrkA/hd.mp4?zrNPGj-jLRzpG53gXn8-aiOIgZ7uuDgtknrMzHWy-xXMnRWvi8Qaze1sTacQ1NzvoTATeuyGtJclnVzqT43ui10fPwjBB2J3BnAfDnww319QuickPrepPDBstructure preparationprepareprotein-protein complexhttps://video.chemcomp.com/watch/PN2EcUydpKUZH9v3F62Fst🆕 Building polymers using the Polymer Builderhttps://cdn.vidyard.com/thumbnails/47919958/3B3XneY97w3AsFQD16FiNA.pnghttps://play.vidyard.com/PN2EcUydpKUZH9v3F62Fst.html?video_id=47919958&https://cdn.vidyard.com/videos/cxSm4xnsHQWpW6poFav3Cw/hd.mp4?HZoAKjcL_4xJcLIxrArlf901p_cdfnhmJnl-szHx6gv3S4dR_Z1hw2hnPFoDnKFJelYnjq3ENCEwG1brHiOTCdGvJ0iXybgZX41Y3eW_275Small Molecule BuilderMOEPolymer BuilderPolymermultiplicitytoxicityHomopolymermonomershttps://video.chemcomp.com/watch/QTwHtDiaWeqk33CTPDoYqkComputing molecular properties for a database of small molecules using Calculate Descriptorshttps://cdn.vidyard.com/thumbnails/40102048/KEjf2yol5Tetyp1ya0xBYw.pnghttps://play.vidyard.com/QTwHtDiaWeqk33CTPDoYqk.html?video_id=40102048&https://cdn.vidyard.com/videos/06F0l389fJsXKv-g-epfcA/hd.mp4?Yk9_lzcCn9GaBL2zikEPKNy_SplzyLTbE-gtcNBoTG1xqjvP3k3UFibV1DKuwNflsOEtIl_wN605uaAYMOju8pnTPDZL8C-09I3BX_8l258propertyDescriptorsmolecular propertiesphysical propertiesdatabasehttps://video.chemcomp.com/watch/REZRShJWUNru81ryxW8c52Structure-Based Charge Calculations for Predicting Properties and Profiling Antibody Therapeuticshttps://cdn.vidyard.com/thumbnails/40549784/FAb1E-N_LjVZSRY-vfbX3A.pnghttps://play.vidyard.com/REZRShJWUNru81ryxW8c52.html?video_id=40549784&https://cdn.vidyard.com/videos/768rU6hPyVCTqvuLw9dVyA/hd.mp4?Fg2Aj9PW4N75updZeqt0xWZnA8HLE7d72lwP9wew6NZd9cmjQZ-npr2xJ7XuFbRXnxe7Nwtxux-YW0BiS_IluDyU0KcwwQIwCLSEnPz92154hydrophobicitydevelopabilitypI isoelectric pointAntibody modeling modeler validationchargetap ruleviscosityprotein modelingwebinarfvantibody discoverycharge calculationstherapeutic profilingpoly specificitypharmacokineticstherapeutic antibodiesantibody clearancePSRhttps://video.chemcomp.com/watch/RamuDvR9u5C9BxiEyYyAvqLowModeMD: Conformational Search of Macrocycles and Protein Loopshttps://cdn.vidyard.com/thumbnails/40112875/JTm8fm0A8EP8ulY8BUiWsA.pnghttps://play.vidyard.com/RamuDvR9u5C9BxiEyYyAvq.html?video_id=40112875&https://cdn.vidyard.com/videos/xqjtRrOgv-KiFI4obBxlxA/hd.mp4?t2sxzph2kR-K_qIta0Beu2V8_zySeWvdPW7sBIvWrYdPuloXZGgUiT3CDJ5l4j0FuQaHQzGj0Vfdg73M5pokeIJcjrOVKqtI7XXJ_oEz2894LowModeMDmacrocyclesconformational searchConformational SearchLowModeMacrocyclesMolecular DynamicsLoop ModelingPeptide ModelingBornwebinarprotein loopshttps://video.chemcomp.com/watch/SNWC6pttWo3nahYSxHNroDProtein-Protein Docking and Epitope Analysishttps://cdn.vidyard.com/thumbnails/46056760/2sqXpGqzdC7qJgrE-rS0Yg.pnghttps://play.vidyard.com/SNWC6pttWo3nahYSxHNroD.html?video_id=46079308&https://cdn.vidyard.com/videos/azhBq9OUPyBpF_KDXlmJZw/hd.mp4?L0X-2JL5yJ_HSOS1-6fAouAIl0jLWTRCRji8KTKdTDypKwog-XO4oZFbqbGhsF8u-g4mT0GhNexy-XA_nLEJ23WlizjjQzeOwP4YBa_Z572structure-based drug designinteraction analysisdruggable sitesepitope mappingcomputational biologySBDDprotein-protein dockinghttps://video.chemcomp.com/watch/SvymyfYNtf9Bet5bTLDy1FTemplate-Guided Docking of Small Molecules to Explore R-Group Substitutionshttps://cdn.vidyard.com/thumbnails/40111319/j9iKhKWvjBp0kKwA12QicA.pnghttps://play.vidyard.com/SvymyfYNtf9Bet5bTLDy1F.html?video_id=40111319&https://cdn.vidyard.com/videos/ho0Ldc1VP_J4tbMVxl9-zQ/hd.mp4?qmpSbCJtWhEePei-Iatw_eJ8XKmusPk9g9Y5E_An0PxonFPQ90OqbExfhNMKtKdnhBVpqfZ5xHSPyTlv6FfngCpkRKkGtObRlCj_FtMT3050dockingDockingPharmacophoretemplate-guidedSARMOEsaicAffinity ScoringsmartsRgroup explorationvirtual screenTemplate guided dockingEGFRHTSKinaseSketcherProtein Familieswebinarhigh throughput virtual screeninghttps://video.chemcomp.com/watch/SxGdojMqWUG2EMYQ3awStQBuilding molecules using the Small Molecule Builderhttps://cdn.vidyard.com/thumbnails/41118533/xT4-RLlOlanZ-1IL3YLMvg.pnghttps://play.vidyard.com/SxGdojMqWUG2EMYQ3awStQ.html?video_id=41118533&https://cdn.vidyard.com/videos/bTMc8iv_B2jsnQY5F2jLMw/hd.mp4?UVl43MAstW7g8NZKesLwmr3_lvdAqZpkLeRWdjsmMkWWRLMcULW4tCLgaoKyrEgowRUddrO1Wn6gp6U2QqH0O0W09AliayuJ9BER24H5359protonation statesSmall Molecule BuilderstereochemistrystereocenterprotomersSMILEStautomerschiralityionization statessmall molecule buildermolecular structuredidanosinetautomer explorationenergy minimizationhttps://video.chemcomp.com/watch/TBuZv3jhytVKynoF2bhCCSSuperposing Proteins on Structural Motifshttps://cdn.vidyard.com/thumbnails/39493233/0cpF-Tb6nQybUpbBpwpHbQ.pnghttps://play.vidyard.com/TBuZv3jhytVKynoF2bhCCS.html?video_id=39493233&https://cdn.vidyard.com/videos/RY7Y_zoKPvVc_vryk8x8iA/hd.mp4?cMHjfYTFkxh93cVGb30v7k0X6L1yJLe1CH0HvEsq69LbBOZecxQrntNEji4rueW57-Tf80OJrBz3y8GT3Jp9o5WfOZmcfZ0eYlKOe9nQ486alignmentAlign/SuperposealignsuperposingaligningsuperpositionSequence EditorsuperposeSEQsequence similarityRMSDdendrogramhttps://video.chemcomp.com/watch/UD18coxPR9GW3NPy9eGMoUVirtual Mutagenesis: Protein Builder and Protein Design Applicationshttps://cdn.vidyard.com/thumbnails/39491350/42eLG1oMZ6HrXa2eqC06fw.pnghttps://play.vidyard.com/UD18coxPR9GW3NPy9eGMoU.html?video_id=39491350&https://cdn.vidyard.com/videos/Xtrrq3pnqrFc-ADYEMmsmA/hd.mp4?PuiEJtJLFJaLApFJDn_9zoJIMEKkUYCF-aojVzgTjXr5fYpsoRvKONGUBtuXV08LWjjTqz78pDlqof6FAEuGQY_llgZsV29nM3u-GptI669antibodiesantibodyProtein BuilderProtein Designvirtual mutagenesisResidue Scanmutateprotein engineeringaffinitymutationsstabilityhttps://video.chemcomp.com/watch/UXPJi6hq2jeUsP96epfFmtNew and Enhanced Biologics Features in MOE 2024.06https://cdn.vidyard.com/thumbnails/45374385/_tk3oz0OTxPKln_Wx3zXiA.pnghttps://play.vidyard.com/UXPJi6hq2jeUsP96epfFmt.html?video_id=45374385&https://cdn.vidyard.com/videos/jvTpuCl_EsqtOiTyS0qiDg/hd.mp4?ugkbNjyYS749hf_yz0XiwT7opYPDeKekagmi370Yb03D1XpfP7ITfs3GqbCBbWWZCeNyaI-wUZJa8alWSlF935ZcuWlU6_Hje1kvNRnl3524antibody modelingBiologicsMOEDrug DiscoveryCADDMolecular Operating EnvironmentCapture Design IdeasAntibody Pharmacophore Virtual ScreeningProtein Docking ValidationInteractive Database Viewer Property FilterMap 2D Protein Patch DifferencesVisualize Ensemble Averages2024.06Protein BindingRNA StructuresTorsion ParametersCapture ToolEHT Methodprediction accuracyreproducibilityvisualization techniquesprotein dockingmolecular modelingwebinarhttps://video.chemcomp.com/watch/VEBZZooArm3F9oKMvNEqvKInteractive Database Filteringhttps://cdn.vidyard.com/thumbnails/45798852/EeuyoS02nchZJQx5QVlnrA.pnghttps://play.vidyard.com/VEBZZooArm3F9oKMvNEqvK.html?video_id=45802391&https://cdn.vidyard.com/videos/wn9Bui3jDygXkYmofnVVUA/hd.mp4?bdkMZV-PckPfjVwYt8mEFmYph_kl36dqTBOzBy3SZo-1SvtBbQ3Sbr9F6bmMl7pF5y6aT-tdjy4piDrbG_4pRH2UliqznrTZot1sEzoy320data analysiscompound filteringCox1Cox2interactive filteringchemical propertiesdatabase applicationmolecular weightS log Pchemical seriesdatabase filteringcompound selectiondata visualizationhttps://video.chemcomp.com/watch/VQcQprj2aGcw1rLoXhp6N2Pharmacophore-guided Biologics Virtual Screeninghttps://cdn.vidyard.com/thumbnails/46323273/NIaUiJiwCgHIX8jmHQGSCQ.pnghttps://play.vidyard.com/VQcQprj2aGcw1rLoXhp6N2.html?video_id=46373602&https://cdn.vidyard.com/videos/Ywio4q51m2oQ_pPEAwnu7Q/hd.mp4?IbQTNma_d2wigmMm7Vvjd_DBKvaRFH3-rKfdgih2E00olmKIbYcwFse90IOagsgNypruXRd2y19HizMqXdl5IueEBgPC031v1-DKZ4qK513ligand interactionsextended Huckel theorypharmacophore searchunusual chemistriesquantum approachreceptor multipliershttps://video.chemcomp.com/watch/WC7cfvFftPmCjXPGZiyHtbAntibody Modeling and Developability Assessmenthttps://cdn.vidyard.com/thumbnails/40112098/vAPaAMP6lwxxQijGRsZYqQ.pnghttps://play.vidyard.com/WC7cfvFftPmCjXPGZiyHtb.html?video_id=40112098&https://cdn.vidyard.com/videos/VtZe84dy6XRrwhazzI6eCg/hd.mp4?Rs8RDDWJ61Tx5uUHY3BTUZ_zfcFsK3tujednEY68_84YKhuBiVA1mx5XmzUNgjZFPQXkFxRl3lr3TvMb00SGJ1PK-pPL0PC-SkPpcVwh2442Antibody homology modelingTemplate loop searchingIdentifying liabilitiesAntibody project searchHigh throughput antibody modelingCalculating protein propertiesDevelopability analysishttps://video.chemcomp.com/watch/XECQAkdQRoTwwbUnm6BT4XFragment Based Drug Design - Link Multiple Fragmentshttps://cdn.vidyard.com/thumbnails/39492445/OlcR484O_lxKR1L0w6wi_g.pnghttps://play.vidyard.com/XECQAkdQRoTwwbUnm6BT4X.html?video_id=39492445&https://cdn.vidyard.com/videos/jrTd-kJnULmxeoUUF9CEMw/hd.mp4?sDvEzydGw2_swEsm_v2j6zg95h6m_oSiSrWyIYLF3C-Ukq2ls6KsuBnEw7jxcz_we1JfgN74jyA4pIRK0p8ClaHXN0_ccro218AX7UjV730fragment-basedfragmentsFBDDlinkinglinklinkersconnectingconnecthttps://video.chemcomp.com/watch/YEBKXt1Sh8FxfitksGWziWMatched Molecular Pairs for Interactive SAR Analysishttps://cdn.vidyard.com/thumbnails/46523470/m5ZmhU8W86EOYtpWvHbOqA.pnghttps://play.vidyard.com/YEBKXt1Sh8FxfitksGWziW.html?video_id=46523470&https://cdn.vidyard.com/videos/RQf0uPYLcqaf4SBhzNMrjQ/hd.mp4?cNcEzRk-5RQTL6i1f3-VMR2Oi7O3aCcntPB5g-mi7Tq3QoJNNSVWUnUGsMOBZb1wutWMFk77u_1570fZ51_i1ubJWCCvCG_t12yxwvWh609bioisosteric replacementsSARMOEsaicMMPMatched Molecular Pairsactivity cliffsSAR analysisCOX2COX-2https://video.chemcomp.com/watch/ZzeJu5KQFQpHwAoLpju6dsPSILO: Streamlined Protein Family Analysis and Refinementhttps://cdn.vidyard.com/thumbnails/40549703/JIKLxT8TbBK6GGtQY0GIYQ.pnghttps://play.vidyard.com/ZzeJu5KQFQpHwAoLpju6ds.html?video_id=40549703&https://cdn.vidyard.com/videos/Zhp326wu3w2FwAMXdodT5Q/hd.mp4?sDgWL0BS-6o-nZtaMwtad66eGu1xMGPjNBfoktV6vapNo0RgWYiPRPVO8eVls1iT5Ug8-OvRI9m6Vs_YortR9KoEgDXuZEur9GEGspP_2972MOEPSILOAlphaFoldMOE Project FamilyPSILO Project FamilyStructural Datapocket searchwebinarhttps://video.chemcomp.com/watch/aMMmhQrqjYaCu7GkTP9ewhMixed QM/MM Methods: MOE and ONIOMhttps://cdn.vidyard.com/thumbnails/40550375/h6Ck4oUrQ75tTB15c7P8YQ.pnghttps://play.vidyard.com/aMMmhQrqjYaCu7GkTP9ewh.html?video_id=40550375&https://cdn.vidyard.com/videos/rogOgYnq5cx03DeC86hBlQ/hd.mp4?RTZxnsmUOCU_ipxfVN6QgqtFeqqbrkYEJG48s-hrUcXz_q76ozw8NmRFSiRkix1OboYp0OQNTLFqClujNyp-A4unQ91SrpQqEdazjuQ92462torsionQMMOESmall MoleculeGaussianQuantum MechanicsMixed MethodsONIOMQM/MMprotein interactionsmolecular modelingquantum mechanicsQMMMinhibitor developmenthigh-performance computingwebinarhttps://video.chemcomp.com/watch/b3NH8mTsqzqccamcMebndJ🆕 MOE license server installation for Machttps://cdn.vidyard.com/thumbnails/48247578/oBEkLaI7ezBO42BW9efHRw.pnghttps://play.vidyard.com/b3NH8mTsqzqccamcMebndJ.html?video_id=48247578&https://cdn.vidyard.com/videos/no4nhTYUOfbNpcma38mV5A/hd.mp4?gKtpddYfg6VAoer8n59xXVxSyZlhzOksAU-X3Evjka7GDIjMK1EF2Qq2yV4SwdIcC1JEGiTk4WuC4RoxtHkCHe8qV_Fd12VeWwiH-zJN476MOEMOE licenselicensenetwork setupMacMOE installationccgchemical computing groupinstallserverFlexNetFlexLMhttps://video.chemcomp.com/watch/ccB5YbwWwAiKK2vK3JiE6ZTemplate-Based Dockinghttps://cdn.vidyard.com/thumbnails/39491581/dmIwj1lPNrXW9JBrr_hepg.pnghttps://play.vidyard.com/ccB5YbwWwAiKK2vK3JiE6Z.html?video_id=39491581&https://cdn.vidyard.com/videos/Ob5t-PHJppS9hExwdW_GvQ/hd.mp4?bFwkTObhOiy5SLFvZ1sO_wGxDS6TdYtIm7d5WtvOlkro_izeXdrp0hoY4ceZTcD3XAwsdQFnHWGUptvgRomNlXEl4pJyXZzeGtWCuSS0881Dockscoring functiondockingbinding pocketscorescoringactive sitevirtual screeningligand interactionssubstructuretemplate-guidedscaffoldtemplatetemplate-basedcongeneric seriessimilarityinduced-fit dockinginduced-fithttps://video.chemcomp.com/watch/dFwXhrb9s4oZnAwFNRd94pReverse Fingerprints (IV): Application to Motif Detection and Pharmacophore Query Gener...https://cdn.vidyard.com/thumbnails/40549975/KA7IjL_HOmv9te18pnV6Zw.pnghttps://play.vidyard.com/dFwXhrb9s4oZnAwFNRd94p.html?video_id=40549975&https://cdn.vidyard.com/videos/qGrliNj620CeIQtjJcrcRw/hd.mp4?70VCDGrNcDRqIAws6nOaumjoeb7gmKZ7q_tXRf6vbksUa5uG40k5t9zqXQh7qS0DWOa9J8Kv4xc_TmpdET_ekbF7ehmVpI8hEGWucBX-2515Ligand-Based DesignMolecular FingerprintsPharmacophore searchingpharmacophore querieswebinarmotif detectionconsensus pharmacophoresligand densityreverse fingerprintingpharmacophore modelsatom scoringhttps://video.chemcomp.com/watch/dNzhRZCrwDhkRTinwHhjp8Modeling Ternary Complexes with Molecular Glues: Making Sense of a Sticky Situationhttps://cdn.vidyard.com/thumbnails/40549674/k6miW1MpHYAIbBqGWpdK8Q.pnghttps://play.vidyard.com/dNzhRZCrwDhkRTinwHhjp8.html?video_id=40549674&https://cdn.vidyard.com/videos/1yoQIwLjoesr4rpnHVdMTw/hd.mp4?uQRGGDSQ6rmmTUL6cZygVetsls0BBW49mGZPUTNtJn4RH5x5OaSdYCT--GHQwI9m5LKsJj9EP9zY5M14g4jcoth3nHWgAbQHttdsJ_NH3271Heterobifunctional DegradersTernary ComplexesTargeted Protein DegradationMolecular GluesMethod 4BProtein-Protein DockingBifunctionalsPROTACswebinarprotein-protein interactionempirical datatructure predictionhttps://video.chemcomp.com/watch/erTW9yWquLc74Tca7XCcgFPractical Guide: Set Up MOE High-Performance Computing on AWS Cloudhttps://cdn.vidyard.com/thumbnails/40550317/imVwpNCSsnZwhC_5uFSUAA.pnghttps://play.vidyard.com/erTW9yWquLc74Tca7XCcgF.html?video_id=40550317&https://cdn.vidyard.com/videos/RDszWoP9G58f2bZBqz7ApA/hd.mp4?1Bmh_XH2MzCh7TWrWVAWKkXUcsTPSQHPK3w423qZUxcR9kPA5Nr-ErkBYgpK9KTbMzL5RIv8IIuqL5qhXr4ksy-rsZ3qs88eJCGxLM1Q3568molecularmodellingdrugdesigncloudcomputingparallelcomputingscalablehpcawshighperformancecomputingclustercomputingsetupinstallationwebinarhttps://video.chemcomp.com/watch/euDbu3dMSAhx6a9rD9LocKDevelopability Assessment & Property Prediction by pH-Dependent Conformational Samplinghttps://cdn.vidyard.com/thumbnails/40111745/cAQjoS0985lHq85A3MDB2w.pnghttps://play.vidyard.com/euDbu3dMSAhx6a9rD9LocK.html?video_id=40111745&https://cdn.vidyard.com/videos/u-3j_W-io2aXCHYDDiROQw/hd.mp4?S_eUP3xTk5mqmgZHNZAI0PWfgrnhGBzkJZtwUKQZpq6pMa4XsFiD7h5GhXiTENxS1Vo1hqSRim5G1eYgpwmCzkEBQHmr2Qgs7YZjnWZP2251hydrophobicitydevelopabilityBiologicsproperty predictionmachine learningsamplingMOEQSPRwebinartherapeutic proteinPKA predictionreactive liabilitieshttps://video.chemcomp.com/watch/g2sdwMv2Jk7bqpPm5RDGjHFragment Based Drug Design - Add Group to Ligandhttps://cdn.vidyard.com/thumbnails/39492692/nIYbSExVlKujxa1PE1jadA.pnghttps://play.vidyard.com/g2sdwMv2Jk7bqpPm5RDGjH.html?video_id=39492692&https://cdn.vidyard.com/videos/H_i042DbA1uQIaoRNP0Z9g/hd.mp4?JRNAY7MBPW0ShxUglfpSBkD4TyimsLnvyZDVzpUrY8Q1eaeEp8LEEqS0bZ0nbH0PN_t6y7u8l5BIXhzxtWnCInabeXr16ta5HG7QD50M806analogsanaloguesgrowR-groupsfragment-basedsubpocketfragmentsFBDDgrowinghttps://video.chemcomp.com/watch/hDryETJKCWBEw5D3HYGncEInteractive superposition of two or more molecules using Superpose Moleculeshttps://cdn.vidyard.com/thumbnails/40102040/s0qyz7hwkQF2rY0CXOQvRA.pnghttps://play.vidyard.com/hDryETJKCWBEw5D3HYGncE.html?video_id=40102040&https://cdn.vidyard.com/videos/tPUTPi-aEXrxgfIZBnni1Q/hd.mp4?11dwlqNA4b_e3XpTcucAS44nOG-mgy4botOd4C2qc1BB7tsVd1hOWTvIdT8d3OcGpiXmsYDJdYPqrs4K3hIa2LNvLyvJb_L8vEw-SR33155alignmentsuperposingaligningsuperpositionsuperposemolecular overlaystructure overlayhttps://video.chemcomp.com/watch/hvgFwQqySyGbk3cFB4u9qg🆕 MOE Project for Organizing Structural Datahttps://cdn.vidyard.com/thumbnails/49776576/1W__EJxlvTivxF3lctvnog.pnghttps://play.vidyard.com/hvgFwQqySyGbk3cFB4u9qg.html?video_id=49781352&https://cdn.vidyard.com/videos/rTPD_9lIkIrZyyzZwbnZlA/hd.mp4?vXfCWkxEXQjetbg8W3GiVmP-SgFwEaO5Z-QbTCvrWKjB1cQyz_RBOYtWPM6hGoYWA0dpURRHRuNTrNuDY_3O4zKUAntQjWg77CDuE4uf458structure-based drug designVirtual screeningCheminformaticsMOECCGCADDMolecular Operating EnvironmentChemical Computing GroupSBDDMOE ProjectProject FamiliesSearch Paneldrug designprotein kinase family3D structuresComputational chemistryMOE tutorialMolecular modelingDrug discovery softwareSmall molecule modelingStructural biologyProtein modelingDrug discovery workflowBiologics modelingProtein structure analysisDocking workflowMolecular data managementResearch data organizationhttps://video.chemcomp.com/watch/i3hUvYD6bMBcBpjjh3Sx4vUsing Surface and Maps to Understand Properties and HotSpotshttps://cdn.vidyard.com/thumbnails/41360502/3ajAfWJ6hL0_U4pBnV17nA.pnghttps://play.vidyard.com/i3hUvYD6bMBcBpjjh3Sx4v.html?video_id=41360502&https://cdn.vidyard.com/videos/R7VJXmuFADObTMx8Gu2Dgg/hd.mp4?hnEf3qvaAGqWm-0rCevFimd1sY-8CMtzMTqCwo_vUQlagUE09NiqPpYXUuKaTDUS3YOZj7Zp9JgadoAUPP3admyjb9DOQKJOWbjCxaXS487Protein PatchessurfacesInteraction SurfaceProtein-Ligand complexMolecular SurfaceConnollyElectrostatic MapsRNA-LigandConserved StructureRHSmolecular analysismapshydrophobic regionshttps://video.chemcomp.com/watch/j8MJPjQ7abznhnqqyTAsskFragment Based Drug Design - MedChem Transformationshttps://cdn.vidyard.com/thumbnails/39492256/d-N-u3SzxNnBNOj9wTkHPg.pnghttps://play.vidyard.com/j8MJPjQ7abznhnqqyTAssk.html?video_id=39492256&https://cdn.vidyard.com/videos/d3Y5hcvL0anAQq_ZU7Sjhg/hd.mp4?D7DoFdi-s6BEaTyjTPog3tH5tvKtg81QqhcoxfLHWz_dUPD8NvNJfsBBA3N-Glj8ZfOn87GJDfJeYFN67PDI7fnukzh9PgNICIcoQsOg644analogsanaloguesfragment-basedFBDDrule-basedmedicinal chemistrybioisosteresbioisosteric replacementshttps://video.chemcomp.com/watch/jLSeWu9X4kHitghELDtKvYX-Ray Crystallography - Structure Preparation, Electron Density and Solventhttps://cdn.vidyard.com/thumbnails/42742649/UVwJdrjER3lBUTrGHpHluw.pnghttps://play.vidyard.com/jLSeWu9X4kHitghELDtKvY.html?video_id=42742649&https://cdn.vidyard.com/videos/l7vwpiASDx62H6cQWYZigQ/hd.mp4?yZN6oe34quPZZNZqfxIvTwCzJovKTuvzyI1DKqMg5rIpAKlSvX_mgq5apxLW8-1ukOtB73OM1hz-t1zo--KXYgJ3HQWDfWTesEECREtJ3325Structure preparationDrug DiscoveryCADDSidechain rotamer explorationSolvent analysis with 3D-RISMElectron density mapsStructural BiologyProtein DNA/RNA ModelingX-ray crystallographysolvent analysiselectron densityprotein modelingmolecular visualizationcrystal contactsligandprotein flexibilityasymmetric unitligand designcrystallographywater moleculesprotein interactionswebinarhttps://video.chemcomp.com/watch/jMbR79BBtsjmp5wz64ETezFree Energy Calculations with Thermodynamic Integration in MOE using AMBERhttps://cdn.vidyard.com/thumbnails/40550036/qJcn_gMCTqBYU14nPqumoA.pnghttps://play.vidyard.com/jMbR79BBtsjmp5wz64ETez.html?video_id=40550036&https://cdn.vidyard.com/videos/44OyvLpM-k22de3XfotVvQ/hd.mp4?-tO1JIGswESo-NHBfwPLg-2aNUACg1f4hgfeYVoDDiektMm_Gu9GdMsS8FzTbVUKqP7OWMXqULZOUCcjFia4oHFADvVFzr7rWQrunDOU3630MOEsimulationHPCRelative Binding Free EnergyThermodynamic IntegrationAMBERRBFEGPUSmall MoleculewebinarMethodological ContributionsData AnalysisSimulation PlanningFree Energy CalculationsP38 Map Kinasethermodynamic integrationhttps://video.chemcomp.com/watch/jzKXybdHk37AWJYE8FvtmQProtein-Protein Docking and Epitope Analysishttps://cdn.vidyard.com/thumbnails/40111553/JB-EDgYOvY-c2TMG9XSbwg.pnghttps://play.vidyard.com/jzKXybdHk37AWJYE8FvtmQ.html?video_id=40111553&https://cdn.vidyard.com/videos/LIS2nh9IfIUF55YMYK4X1A/hd.mp4?BCNj_xnGEn-FNuLq9MP6BRAkROmsLZi9suwqPGUV82iUYWwZijhWTzeCY9KeWiRE1WgudXbePtT6CwAONLheYuSu4kbRyh-YCfLsnKja1796dockingEpitope analysisProtein Ligand Interaction Fingerprintsantigen-antibody complexesPLIFclusterhydrophobic interactionsensemble approachinteraction fingerprinthydrophobic patch potentialwebinarbiophysical dataclustering analysisprotein-proteinhttps://video.chemcomp.com/watch/k2GbLcLte2rt2yUfLuNgy8Pocket Similarity: Are Cα’s Enough?https://cdn.vidyard.com/thumbnails/40549998/m4hPES6CaSl55i8EVkyMcg.pnghttps://play.vidyard.com/k2GbLcLte2rt2yUfLuNgy8.html?video_id=40549998&https://cdn.vidyard.com/videos/M8Vf92I1dnMEAP5mOdEBRg/hd.mp4?kuC0W8nGK8jMe1EyDh2UR88PFRvB3f3Q4ssihIwIUq6nGCCn6tNUNeGFWnoficyAKG7M0KoD3YkR9x3c8UkdfDd5J4GW6vg_z039BAiY3333similarityPSILOextreme value distributionclusteringpocket searchDrug DiscoveryProtein StructurewebinarDruggable Binding SitesAlpha CarbonsPocket SimilarityLigand BindingProtein ClusteringBioinformaticsComputational BiologyMolecular Dockingquery builder3D interactionmacromolecular structuresearch functionalitystructural biologyhttps://video.chemcomp.com/watch/kZhaHoL6CCfAsqmJrL448bFragment Based Drug Design - Scaffold Replacement; Fused Ringhttps://cdn.vidyard.com/thumbnails/39492086/ksvUnPTZRUzcdZtzF1GqoQ.pnghttps://play.vidyard.com/kZhaHoL6CCfAsqmJrL448b.html?video_id=39492086&https://cdn.vidyard.com/videos/eDjnhFu07TOi-h2VK_9drg/hd.mp4?pIMUSvGlCZVNdEobX8RmI62c6q3wzPEZrs4AKXWhjcW0mx15fVJxNZoym9Gl20yTqLwOVo4mJTdT9qqXbVO_DgxJsUx8u0ZAjzUx3cm-664analogsanaloguesfragment-basedfragmentsFBDDlinkersscaffold hoppingsubstructurescaffoldshttps://video.chemcomp.com/watch/mEGY24Z6DfWCowo9iqFn7U🆕 Generating 3D conformations for a database of small moleculeshttps://cdn.vidyard.com/thumbnails/49948556/1G6kjkIbNjvisCjhWY7sYQ.pnghttps://play.vidyard.com/mEGY24Z6DfWCowo9iqFn7U.html?video_id=49959549&https://cdn.vidyard.com/videos/6ddoOg1LuRO0_ZCgtL0dvA/hd.mp4?rdXs4Jf_elGV6iUwyczmAMinie8ifZhLTRrCyYpPuUnb4vOcSMNWr0Tldo7KKx5UAXfzCol01TPcF0WFeZUBbgrQK6_FiRkOGGQjL8qH285LowModeMDMOEconformational searchLowModeCCGMolecular Operating EnvironmentChemical Computing Groupsmall moleculesliganddrug designSuperposingconformational databaseLBDDligand-basedhttps://video.chemcomp.com/watch/n6WYJLeE6tfXprejbbdMm4Fragment Based Drug Design - Scaffold Replacementhttps://cdn.vidyard.com/thumbnails/39490581/htBG9pMVMN89kM83-2kHpg.pnghttps://play.vidyard.com/n6WYJLeE6tfXprejbbdMm4.html?video_id=39490581&https://cdn.vidyard.com/videos/DuN__lzy0_qmTm93-0Wt9g/hd.mp4?Q0xt6Ez13qZRe2LG1tPkiLeCihAW247qOqOfHcXGCFj57Kq-bbRV98uuNnHGEw2cLxPRbEEGQJCvu2Gn8lYbuelvEe-raVr56HOl7sC21017analogsanaloguesfragment-basedfragmentsFBDDlinkersscaffold hoppingsubstructurescaffoldshttps://video.chemcomp.com/watch/oamYtMVNqacZ9dnJLB1C5vCovalent Dockinghttps://cdn.vidyard.com/thumbnails/39491146/P9r1Cl9YEDkm-7rOsIRqPw.pnghttps://play.vidyard.com/oamYtMVNqacZ9dnJLB1C5v.html?video_id=39491146&https://cdn.vidyard.com/videos/DN5J735El2SnP6wsZJSppw/hd.mp4?zGW3WR4biHyk1jF3zd4rWSM8UiP0J4PcsqUNZ5NlyxbubeBeFb-R0wYds5AJk6zlPoYSl5w8okzLNiSYwxmdjCpTz98qzXbao0Nxe4kE806Dockscoring functiondockingbinding pocketscorecovalentscoringreactionactive sitevirtual screeningligand interactionshttps://video.chemcomp.com/watch/pw897CpWqzoZkRwVwtabVcFrom Structure to Dynamics Simulation: Running & Visualizing MD Trajectorieshttps://cdn.vidyard.com/thumbnails/40550030/SRiOdNytJ0v9ioJfEXjozw.pnghttps://play.vidyard.com/pw897CpWqzoZkRwVwtabVc.html?video_id=40550030&https://cdn.vidyard.com/videos/a46di1J63nQbwx_fTCceKQ/hd.mp4?SyLrPWwAcKQDIBefe-Hrw7Vu8R5HWN5BnOrOgX-zAS9mZtwxS0AnVpuL9bvnyOPmdGx22r4huwBsSZa0yn-HhkhEQiK6CNF6gakmCrn81994Protein PropertiesProtonation stateAMBERMolecular DynamicsSolvationStructure preparationMDSimulationEHT parametrizationRestraintsTethersNAMDDynamicsTrajectory AnalysisProtein-Ligand ComplexSimulation SetupData VisualizationLigand Protonationhttps://video.chemcomp.com/watch/q17WV5nDHy4DQ4LHK7EtkBAnalyzing and comparing Protein-Ligand complexes using Ligand Interactionshttps://cdn.vidyard.com/thumbnails/40102054/h8wE5KhAlKcVFD9ycZ_CMQ.pnghttps://play.vidyard.com/q17WV5nDHy4DQ4LHK7EtkB.html?video_id=40102054&https://cdn.vidyard.com/videos/oJuTN4Pl6GU_MpJ17TdEoQ/hd.mp4?MEUCWSvoOB0nYxoc0HFVfEmpSRqd4oxWyU2iH6tF3u42EUv-XNoNIRY1r0I7UTfWzYPTGhoezQp4R552-Zivt_31KBeDKo9HuYx3KSdx279Protein-Ligand InteractionsLigand InteractionsH-BondsContactsHydrogen Bondshttps://video.chemcomp.com/watch/qFyMs9KHdNc5Pn8DGSF1MPBuilding molecules using the Protein Builderhttps://cdn.vidyard.com/thumbnails/41212284/dlGucMrDpKUu1YVkmbOolw.pnghttps://play.vidyard.com/qFyMs9KHdNc5Pn8DGSF1MP.html?video_id=41212284&https://cdn.vidyard.com/videos/ABAfWI1UZgVLM-xz1PAm5Q/hd.mp4?ciLBJhE_2WV10GpKY-PZzKceRhV6hEa3TG-Qg8hrqx5rYIHU9vB-aHxaS3eDkib1pCNhGc-2zTJKkocIqHew6BpEfZYF1fc4KtamB-HZ269Protein Buildermutatebackbone geometrysecondary structuremutationappendrotamersprependprotonation statescapping groupsstereochemistrypeptidemall molecule buildermolecular structurehttps://video.chemcomp.com/watch/qqH5jfPApdecuts7YJjDh4Antibody Modeling and Developability Assessmenthttps://cdn.vidyard.com/thumbnails/39491265/HIRqIRk1_G1OvC-on9PUVQ.pnghttps://play.vidyard.com/qqH5jfPApdecuts7YJjDh4.html?video_id=39491265&https://cdn.vidyard.com/videos/vlEw9ZVHD8sYTc-M5ZLVvw/hd.mp4?JCaVYFoCCDJ23wN6y3IFGzbafzr8tXvgHOihoWv93AHG8iNA2B8ADqIFrSr73Y7u7b2YdOI3pQAkbuUZ5svHjAKOAzfxjjoZmiS-eaHD1465Protein PatchesaggregationdevelopabilityFvAntibody Modelerantibody modelingantibodiesFabannotationsannotateliabilitiesliabilityProtein PropertiespropertyProject SearchAntibody Databasehttps://video.chemcomp.com/watch/rPHJGC8VoD21zhgMB4iZnsDatabase AutoPH4: Pharmacophore Analysis of Multiple Protein Structureshttps://cdn.vidyard.com/thumbnails/40549833/h2MjOlBAD83OvARxYI5BNg.pnghttps://play.vidyard.com/rPHJGC8VoD21zhgMB4iZns.html?video_id=40549833&https://cdn.vidyard.com/videos/9Ty0OYtWxudfRGZvSHL65Q/hd.mp4?bqaWqtYE6Em82SZ00N6lO_OV6E8hU3bPBhR5iwVJZ7IvSubTZSL-nG0TUlga-TDoBFePN0fM4FoTReQ4KsjW6Q0Hneg2ZknXH1BX1uHq2333webinardrug discoveryprotein structurespharmacophore analysisbinding sitesprotein databasesAutoPH4consensus featuresselectivity mappinghttps://video.chemcomp.com/watch/tRxcjs5AXmeVMKAd9CitfRHow to Align Two Small Molecules Using Flexible Alignmenthttps://cdn.vidyard.com/thumbnails/37312281/IhmsA4gUXIr1dIhgKPc3WA.pnghttps://play.vidyard.com/tRxcjs5AXmeVMKAd9CitfR.html?video_id=37312281&https://cdn.vidyard.com/videos/QbWEufYnT_WgJZkCP3JT2A/hd.mp4?bx2rpA-pxRDQBkegAnaEx-CIkGMCFPACe2Sx2wxOcYVwYtF93HxoBNUPksGmVjP_dGez0wLVtm0sWjWRshDs5sauloEPU6GoZ213x4bj293alignsuperposingaligningsuperpositionsuperposeFlexAlignFlexible Alignmentmolecular overlayconformationsstructure overlaysmall moleculesflex alignhttps://video.chemcomp.com/watch/tfTRG5mGP32f2ADfciTXzBIntroduction to MOEsaic for Interactive SAR Analysishttps://cdn.vidyard.com/thumbnails/46310118/nXkCt-bUrVY-PBE8I-EaKw.pnghttps://play.vidyard.com/tfTRG5mGP32f2ADfciTXzB.html?video_id=46310118&https://cdn.vidyard.com/videos/AI5Qkhej45VNHW7mpVjoBw/hd.mp4?hYPEQTmsFbgQxcWBz_ERYJ7guW5J6OicUuHv6pz2niwtjZ6a-1z6AWPJuHPbVeeGjw5de-75RGv1DZO06z9Q0HWYuXeLS0oJ-2MNj4cy589MOEsaicinteractive cell analysisTanimoto scorechemical motifssubstructure searchdataset configurationsimilarity searchhttps://video.chemcomp.com/watch/totck7yUHqEmGR1dhfoLQQMOE license server installation for Windowshttps://cdn.vidyard.com/thumbnails/45725294/up1LbXT7C4psN-Pl8O7dFw.pnghttps://play.vidyard.com/totck7yUHqEmGR1dhfoLQQ.html?video_id=45766669&https://cdn.vidyard.com/videos/vtcfLKstoBAs7bqkpHe-jA/hd.mp4?jeiLdSpEi_vNBb19u7-JXKyREV17Y2ewVYiSKjdrPa5K8lqzLAy48nzHQ8drhoyefaWl4S1CZWN-s-SXgt0QrKntlVonVVIsjLX174hN533MOEinstallationMOE licenselicenseWindowslicense serverconfigurationFlexNetFlexLMhttps://video.chemcomp.com/watch/undLt7XrNBCj48bbQB3JZAAdvanced Protein Alignment and Superpositionhttps://cdn.vidyard.com/thumbnails/39493356/0_E9wVGJBDWkLdBGcZ0J0w.pnghttps://play.vidyard.com/undLt7XrNBCj48bbQB3JZA.html?video_id=39493356&https://cdn.vidyard.com/videos/O_6zbdvMiIs6_OpZc7xJ8w/hd.mp4?bMJxb9EoCbB6ScjmPiCG91YPW04WLzMU0EaPTcct-qbCP7bEC-rFcQRYlvUxNEQQYMf61Vr7smnEb7XK4c-5K8dAzySJMwH9Mzq9pCgH978alignmentAlign/SuperposealignsuperposingaligningsuperpositionSequence EditorsuperposeSEQsequence similarityRMSDsubunitsdendrogrammultimershttps://video.chemcomp.com/watch/uwxhfdw8Zx7BAZ7BbmbvG3Analyzing protein surfaces for excess charge or hydrophobicity using Protein Patcheshttps://cdn.vidyard.com/thumbnails/39493078/7MhvRyyyjp-Br0Bpu8e6Kw.pnghttps://play.vidyard.com/uwxhfdw8Zx7BAZ7BbmbvG3.html?video_id=39493078&https://cdn.vidyard.com/videos/kfIOwqnbrRpl-jYwe89gcw/hd.mp4?jfW8E5R43NFN24dXKUQK_1jBGmI5vT-Ehbd58ChYHzBmLjxU8SfYY4CmlNxi3mNtoFo1FRLdU2p8LJ9LCUwW5pJ6og1d-T6y1NZuyRj8276hydrophobicityProtein Patchespatch analysisProtein Patch AnalyzeraggregationProtein Patches 2D Mapssurface propertiesexcess chargesolubilitydevelopabilityhttps://video.chemcomp.com/watch/w5MMj7j8Kp89D4C65gJAD4🆕 Pharmacophore Search using Extended Hückel Theoryhttps://cdn.vidyard.com/thumbnails/47090602/k9N1xqGcDqkRFECjcKGmYg.pnghttps://play.vidyard.com/w5MMj7j8Kp89D4C65gJAD4.html?video_id=47119008&https://cdn.vidyard.com/videos/t98GyTHsUjQzNIKnAjnj8Q/hd.mp4?CUQpWsnzGlZFJ2JAcmzWa0IvfDkt2_ulc6nqo2fx1r75WhOh7OLtsiDUlxIWn18vGpVPOKY2816G8pki79Y-k4QOmNoIPE2CcfBbYV7d525ligand interactionspharmacophoreEHTextended Huckel theorypharmacophore searchunusual chemistriesquantum approachreceptor multipliersHückelpharmacophore query editorPH4https://video.chemcomp.com/watch/ww6HstWLBZEkUw66HjDx7HModeling Cyclic Peptides with MOEhttps://cdn.vidyard.com/thumbnails/40549690/SfHT4kXDu7et8ajqkfCDdw.pnghttps://play.vidyard.com/ww6HstWLBZEkUw66HjDx7H.html?video_id=45753618&https://cdn.vidyard.com/videos/Ynu4er9cX4c7AotDN1OVUA/hd.mp4?bA46YZBeuDDL_fl2oT5N7QEA3um9rTEZW_gauBTAdIjPc39OMO0eh0UYEp_VLKy7ehMVua_PNIrAJAUxPfIaly4N9c7ouY6UoRdKAD0x2958Protein PropertiesProtein DesignLowModeMDConformational SearchLowModeMacrocyclesPeptide ModelingCyclic Peptidesmolecular modelingprotein designwebinarreceptor interactionsstapled peptidespeptidomimeticspeptide permeabilitypeptide therapeuticshttps://video.chemcomp.com/watch/xBfx3DkmLV2HVrC3BB8StXAntibody-Antigen Analysis and Mutationshttps://cdn.vidyard.com/thumbnails/39491717/oFtGCxMvWKC6iuR0SNHZfQ.pnghttps://play.vidyard.com/xBfx3DkmLV2HVrC3BB8StX.html?video_id=39491717&https://cdn.vidyard.com/videos/0g6_4ShehbTa48vtsjYHTg/hd.mp4?OPpomoVxbvi5_0O31GuvioC0AH_W7ohCoua2ahpTQtKlbcRiRSQxdbiExUdiDmnudHwGrOaKwysL8-2F2f-R5R8n9aah3BwlpHqdb43-2173Protein PatchesProtein Patch AnalyzerFvantibodiesFabannotationsannotateProtein PropertiespropertyantibodyantigensSurfacesProtein ContactsProtein BuilderProtein Designvirtual mutagenesisResidue Scanmutateprotein engineeringaffinitymutationsstabilityhttps://video.chemcomp.com/watch/xEYETQnHWeuMTPSNjELrwoCreating and Analyzing Focused Mutant Libraries for Protein Engineeringhttps://cdn.vidyard.com/thumbnails/40112578/4U9X17ThO09snXhGN421xQ.pnghttps://play.vidyard.com/xEYETQnHWeuMTPSNjELrwo.html?video_id=40112578&https://cdn.vidyard.com/videos/PJ95dOhOGqM5sZev6nb78A/hd.mp4?rxFywyjmdDSyNq8smOW4Swpl2ARUY9JANQZQcqSinCTnRdT_X3DjPuSK7-3W0efz-4LJ-QfHoxDig39-2G2dxbTlJL72ZX-wglWgCdM92807Protein DesignFocused Mutant LibrariesProtein EngineeringComputational Phage DisplaySample SequenceAntibody Modelingprotein interactionsprotein propertieswebinarmutation analysissimulation techniquesprotein librariescomputational simulationshttps://video.chemcomp.com/watch/xZZ88TSs3e54NaX55juGCxInteractive Structure-Based Drug Designhttps://cdn.vidyard.com/thumbnails/39490583/eQ_zsYL5Y_Okg1DHnYQrGw.pnghttps://play.vidyard.com/xZZ88TSs3e54NaX55juGCx.html?video_id=39490583&https://cdn.vidyard.com/videos/-R22lLx8am6XL2v-UED9cg/hd.mp4?lylKnLIle2gRV3NBaqC_kmnKI6fturemvKplsSLDFAPzOGKVpT9ve7bskzGyDljXfFr2q5o41ZqSJqQX8gav8pdEGCuPaN1_u6rB786v1427Small Molecule Builderbinding pocketactive sitefragmentsoptimizeLigand Interactionoptimizationstructure-based drug designminimizationelectrostatic mapspropertiesminimizesurfacesR-vectorsminimisebuildminimisationtorsiondihedralhttps://video.chemcomp.com/watch/yMJbGiXnfAws3qBNkh78z4MOEsaic: The Application of Matched Molecular Pair Analysis to SAR Explorationhttps://cdn.vidyard.com/thumbnails/40112854/YOU-yy3lBvLxmOyGwZh3ig.pnghttps://play.vidyard.com/yMJbGiXnfAws3qBNkh78z4.html?video_id=40112854&https://cdn.vidyard.com/videos/Gpzpvfr_RFR6StKL9n6bDA/hd.mp4?PEpMVh1KHE6zn9UiwMcNrdoszT08lf74ZmxdtetpA5owX8Rxa2EbhDF2leXUPYjRlIzbTByxY9zWBK5tb3Vua5mm5WSiTj9uAhHhUGsy3315alignmentvirtual compoundsSARproject configurationstructuresmall moleculeshare sessionMOEsaicbox plotscatter plotsmodelsdescriptorsMMPR group analysisMMP ProfileMatched Molecular PairsR group profileR Group FragmentationPair Mode viewactivity cliffphysicochemical spacechemistry aware filtersweb applicationMACCS fingerprintTanimoto similaritywebinarhttps://video.chemcomp.com/watch/yfdzduRZAWueZAwUUCSrZ7Preparing a raw PDB file for use in MOEhttps://cdn.vidyard.com/thumbnails/39492883/3XIaI3oFP5p9SK2nEfBxJg.pnghttps://play.vidyard.com/yfdzduRZAWueZAwUUCSrZ7.html?video_id=39492883&https://cdn.vidyard.com/videos/H6faIG-Mur4mK9NGfmr3Pw/hd.mp4?t7rSBOjFasi8_-BFNBRC78jxYowXSYZRE0MIsfynLwRZfECCmxiW95bXGr6qDAm2odWcBWbkrhYTG111AeOxivgimc7d7xLQBViUtdKJ265QuickPrepPDBstructure preparationprepareprotein-ligand complexMOEhttps://video.chemcomp.com/watch/z3yNbGHFm1eeMET74CGPrkIn Silico Fragment-Based Drug Design: Approaches and Applicationshttps://cdn.vidyard.com/thumbnails/40110490/taqBRXjyMXdM-p4v78VVmQ.pnghttps://play.vidyard.com/z3yNbGHFm1eeMET74CGPrk.html?video_id=40110490&https://cdn.vidyard.com/videos/D2hoWFOhGEdJK8k9SkBO_g/hd.mp4?9CMX1IVAnGaqhhRnHR6uUSMP9cpaHcpGlbDW_yjWAjsuFmfLuXa5TN9VMZZKFgTIp6eHc1US5mLclM66ZrLm792Ed4ri_SYtktI09EYh2680combinatorial librarycombinatorial enumerationanalogsanaloguesgrowR-groupsfragment-basedsubpocketfragmentsFBDDgrowinglinkinglinklinkersconnectingconnectrule-basedmedicinal chemistrybioisosteresbioisosteric replacementsscaffold hoppingsubstructurescaffoldswebinarhttps://video.chemcomp.com/watch/zY1HEV64W34WFV51pUZwSEFragment Based Drug Design - Combinatorial Builderhttps://cdn.vidyard.com/thumbnails/39492596/bI_rbvayWeUxWJv25mqVbw.pnghttps://play.vidyard.com/zY1HEV64W34WFV51pUZwSE.html?video_id=39492596&https://cdn.vidyard.com/videos/ZDSam8pP_ickT9o_PHgAbQ/hd.mp4?rouyxJKYYLUN2Zt-2q-y1ezyXQkRm8TmBv3kS2ZSLgVDIkHH4jPTC0LMaL6rzNgRfziqFhrjfxPK1ZVq5nOnBLY3c5r6dnPkoAGVitQa758combinatorial librarycombinatorial enumerationanalogsanaloguesgrowR-groupsfragment-basedsubpocketfragmentsFBDDgrowinghttps://video.chemcomp.com/https://video.chemcomp.com/categories/3d-molecular-visualizationhttps://video.chemcomp.com/categories/structure-based-designhttps://video.chemcomp.com/categories/antibody-and-biologics-design-2https://video.chemcomp.com/categories/moesaic-sar-explorer-2https://video.chemcomp.com/categories/ligand-based-design-2https://video.chemcomp.com/categories/protein-dna-rna-modeling-2https://video.chemcomp.com/categories/virtual-screening-2https://video.chemcomp.com/categories/fragment-based-discovery-2https://video.chemcomp.com/categories/structural-bioinformatics-2https://video.chemcomp.com/categories/molecular-simulations-2https://video.chemcomp.com/categories/peptide-modeling-2https://video.chemcomp.com/categories/structural-biology-2https://video.chemcomp.com/categories/cheminformatics-and-qsar-2https://video.chemcomp.com/categories/customization-and-deployment-2https://video.chemcomp.com/categories/psilo-structure-databasehttps://video.chemcomp.com/categories/newly-added-videos